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Rudresh Acharya's Lab

Research Laboratory for Macromolecular Crystallography and Protein design

Group Members

Principal Investigator

Dr. Rudresh Acharya

Associate Professor

Postdoctral training under the guidance of Prof. William F. DeGrado, University of Pennsylvania.
PhD., from Indian Institute Of Science, Bangalore.

My research interests are X-ray Crystallography, Protein Design, Protein Dynamics, Enzymes, Catalysis, Computations, De novo peptide design, and Transmembrane Peptides.

Hobbies; building RC Toys; Drone, Fixed wing Planes, 3D-printed Cars

PhD students

Nilima Mahapatra

I'm from Bhubaneswar, and did my masters in Biotechnology from the University of Hyderabad (2016-2018). I Joined Rudy's group in 2019 as PhD, scholar and working on the structure-function-dynamics of a bacterial Histidine Kinase, a part of two component systems.

Ranjita R Samal

I am from Balasore Odisha. I did my Masters and M.phil in biotechnology from Fakir Mohan University. I joined Rudy's lab in aug 2022 and I am currently working on protein engineering by directed evolution to design novel protein that has improved industrial activity.

Hariom Kumar Verma

I joined Rudy's lab in Jan 2023 and I am currently working on protein engineering by directed evolution to design novel protein that has desired substrate specificity and imporved activity. Further, provide structural basis for its functioning through X-ray Crystallographic and Compuational approaches.

Soubhik Das

In Jan 2024, I joined Rudy's group. My primary work focuses on structural insights into transmembrane helical assembly and De novo design of helical peptides.

Kartik Anand

From Delhi, I joined Rudy’s lab in August 2024 with a master’s degree in Biophysics. My research currently focuses on the structural and functional dynamics of Histidine kinases, proteins forming bacterial two-component systems that enable bacteria to sense and respond to their environment.

Int. PhD students

Shivam Pandey

I completed my B.Sc. in Zoology at BHU and joined NISER as an integrated Ph.D. student. My current research focuses on de novo protein design, specifically, I am exploring the structural and functional characteristics of the single-chain due-ferri protein (DFSc).

Int. M.Sc., students

Anjali Krishna

I am from Kerala, currently doing my integrated MSc from NISER. I joined Rudy's lab in August 2023. My work at Rudy's lab is focused on understanding the structural-functional dynamics of a protein belonging to polysaccharide lyases (PL-5).

Yadhunandan S

I am Yadunandan S , fourth year integrated MSc student hailing from Kerala. I joined Rudy’s lab in August 2023 and I am working on “de novo designing of a membrane soluble tetrameric helical bundle protein”.

Satyam Kumar Yadav

I am Satyam, and I joined the lab in August 2024 as a fourth-year Int. MSc student. I am working on protein design, structural biology, and biochemistry, utilizing molecular simulations (MD, QM/MM, docking) and experimental approaches to study protein-ligand interactions and enzyme function.

Adisha Ray

I am Adisha Ray, a master's student at NISER Bhubaneswar, Odisha. My research focuses on the characterization of peptide assembly nanostructures, exploring their properties and potential applications.

Urja Sahu

Hii! I am from Madhya Pradesh. I joined Rudy’s lab in August 2025 for my MSc thesis. I am currently working on the structure-function relation of cytochrome P450BM3 variants that can degrade potential bioaccumulants, and protein engineering by directed evolution of Polysaccharide Lyases using X-ray crystallography, biochemistry, and computational methods.